产品目录

分子量：Approximately 8.9kDa,a single non-glycosylated polypeptide chain containing 76 amino acids.
储存条件：冷冻（-20℃）

概述

Human CCL8,also known as monocyte chemotactic protein 2(MCP-2),is belonging to the CC chemokine family.It is encoded by the gene CCL8.MCP-2 has two homogeneous MCP-1(CCL2)and MCP-3(CCL7).These three MCPs were found by IL-1-beta triggered human MG-63 osteosarcoma cells.CCL8 shares 62%amino acid sequence identity with MCP-1,and shares 58%amino acid sequence identity with MCP-2.CCL8 has chemotactic function for monocytes,eosinophils and neutrophils.In addition,it can also chemoattract activated NK cells.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞96%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The biological activity determined by a chemotaxis bioassay using human peripheral blood monocytes is in a concentration range of 10-100ng/ml.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in 20mMPB,pH 7.4,100 mM NaCl.
内毒素	Less than 1 EU/μg of rHuMCP-2/CCL8 as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	QPDSVSIPIT CCFNVINRKI PIQRLESYTR ITNIQCPKEA VIFKTKRGKE VCADPKERWV RDSMKHLDQI FQNLKP

相关搜索：重组人MCP-2/CCL8，MCP-2/CCL8, Human